A Multicenter Retrospective Case Study of Anaphylaxis Triggers by Age in Korean Children

نویسندگان

  • So-Yeon Lee
  • Kangmo Ahn
  • Jihyun Kim
  • Gwang Cheon Jang
  • Taek Ki Min
  • Hyeon-Jong Yang
  • Bok Yang Pyun
  • Ji-Won Kwon
  • Myung Hyun Sohn
  • Kyung Won Kim
  • Kyu-Earn Kim
  • Jinho Yu
  • Soo-Jong Hong
  • Jung Hyun Kwon
  • Sung-Won Kim
  • Tae Won Song
  • Woo Kyung Kim
  • Hyung Young Kim
  • You Hoon Jeon
  • Yong Ju Lee
  • Hae Ran Lee
  • Hye-Young Kim
  • Youngmin Ahn
  • Hye Yung Yum
  • Dong In Suh
  • Hyun Hee Kim
  • Jin-Tack Kim
  • Jeong Hee Kim
  • Yong Mean Park
  • Sooyoung Lee
چکیده

PURPOSE Although anaphylaxis is recognized as an important, life-threatening condition, data are limited regarding its triggers in different age groups. We aimed to identify anaphylaxis triggers by age in Korean children. METHODS We performed a retrospective review of medical records for children diagnosed with anaphylaxis between 2009 and 2013 in 23 secondary or tertiary hospitals in South Korea. RESULTS A total of 991 cases (mean age=5.89±5.24) were reported, with 63.9% involving patients younger than 6 years of age and 66% involving male children. Food was the most common anaphylaxis trigger (74.7%), followed by drugs and radiocontrast media (10.7%), idiopathic factors (9.2%), and exercise (3.6%). The most common food allergen was milk (28.4%), followed by egg white (13.6%), walnut (8.0%), wheat (7.2%), buckwheat (6.5%), and peanut (6.2%). Milk and seafood were the most common anaphylaxis triggers in young and older children, respectively. Drug-triggered anaphylaxis was observed more frequently with increasing age, with antibiotics (34.9%) and nonsteroidal anti-inflammatory drugs (17.9%) being the most common causes. CONCLUSIONS The most common anaphylaxis trigger in Korean children was food. Data on these triggers show that their relative frequency may vary by age.

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عنوان ژورنال:

دوره 8  شماره 

صفحات  -

تاریخ انتشار 2016